Searching for a way back from everlasting exile, renegade fallen angels Loki (Matt Damon) and Bartleby (Ben Affleck) attempt to turn the cosmological system on its head - unless an unlikely horde of humans can stop them.
Bethany (Linda Fiorentino), the heroine of Dogma is a woman convinced her prayers have not been answered when, out of nowhere, a heralding angel appears in her bedroom and declares her the potential saviour of humanity. Setting off on an extraordinary journey, Bethany meets a host of heavenly and hellish characters, including the celestial messenger Melatron (Alan Rickman), an apostle with a 2,000 year old grudge (Chris Rock), hot-headed demon Azrael (Jason Lee) and heavenly muse Serendipity (Salma Hayek).
In Kevin Smith's comic fantasia, angels, demons, apostles and prophets (of a sort) walk among the cynics and innocents of the Earth and battle it out for the fate of humankind.